Publications

Estrogen signaling in arcuate Kiss1 neurons suppresses a sex-dependent female circuit promoting dense strong bones.
Herber CB, Krause WC, Wang L, Bayrer JR, Li A, Schmitz M, Fields A, Ford B, Zhang Z, Reid MS, Nomura DK, Nissenson RA, Correa SM, Ingraham HA Nature communications, 2019

Associations between vertebral body fat fraction and intervertebral disc biochemical composition as assessed by quantitative MRI.
Krug R, Joseph GB, Han M, Fields A, Cheung J, Mundada M, Bailey J, Rochette A, Ballatori A, McCulloch CE, McCormick Z, O'Neill C, Link TM, Lotz J Journal of magnetic resonance imaging : JMRI, 2019

The Relationship Between Endplate Pathology and Patient-Reported Symptoms for Chronic Low Back Pain Depends on Lumbar Paraspinal Muscle Quality.
Bailey JF, Fields AJ, Ballatori A, Cohen D, Jain D, Coughlin D, O'Neill C, McCormick Z, Han M, Krug R, Demir-Deviren S, Lotz JC Spine, 2019

Measuring and reporting of vertebral endplate bone marrow lesions as seen on MRI (Modic changes): recommendations from the ISSLS Degenerative Spinal Phenotypes Group.
Fields AJ, Battié MC, Herzog RJ, Jarvik JG, Krug R, Link TM, Lotz JC, O'Neill CW, Sharma A European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2019

Suppressed Osteocyte Perilacunar / Canalicular Remodeling Plays a Causal Role in Osteoarthritis.
Courtney M Mazur,Jonathon J Woo,Cristal S Yee,Aaron J Fields,Claire Acevedo,Karsyn N Bailey,Tristan W Fowler,Jeffrey C Lotz,Alexis Dang,Alfred Kuo,Thomas P Vail,Tamara Alliston bioRxiv, 2019

Effects of dynamic loading on solute transport through the human cartilage endplate.
Sampson SL, Sylvia M, Fields AJ Journal of biomechanics, 2018

Contribution of the endplates to disc degeneration.
Fields AJ, Ballatori A, Liebenberg EC, Lotz JC Current molecular biology reports, 2018

Cartilage Endplate Thickness Variation Measured by Ultrashort Echo-Time MRI Is Associated With Adjacent Disc Degeneration.
Berg-Johansen B, Han M, Fields AJ, Liebenberg EC, Lim BJ, Larson PE, Gunduz-Demir C, Kazakia GJ, Krug R, Lotz JC Spine, 2018

FGF and TGFβ Signaling Link Form and Function During Jaw Development and Evolution.
Woronowicz KC, Gline SE, Herfat ST, Fields AJ, Schneider RA Developmental biology, 2018

Publication trends in spine research from 2007 to 2016: Comparison of the Orthopaedic Research Society Spine Section and the International Society for the Study of the Lumbar Spine.
Martin JT, Gullbrand SE, Fields AJ, Purmessur D, Diwan AD, Oxland TR, Chiba K, Guilak F, Hoyland JA, Iatridis JC JOR spine, 2018

Larger vertebral endplate concavities cause higher failure load and work at failure under high-rate impact loading of rabbit spinal explants.
Dudli S, Enns-Bray W, Pauchard Y, Römmeler A, Fields AJ, Ferguson SJ, Helgason B Journal of the mechanical behavior of biomedical materials, 2018

Contributions of Material Properties and Structure to Increased Bone Fragility for a Given Bone Mass in the UCD-T2DM Rat Model of Type 2 Diabetes.
Acevedo C, Sylvia M, Schaible E, Graham JL, Stanhope KL, Metz LN, Gludovatz B, Schwartz AV, Ritchie RO, Alliston TN, Havel PJ, Fields AJ Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2018

Tidemark Avulsions are a Predominant Form of Endplate Irregularity.
Berg-Johansen B, Jain D, Liebenberg EC, Fields AJ, Link TM, O'Neill CW, Lotz JC Spine, 2018

Estrogen Signaling in Arcuate Kiss1 Neurons Suppresses a Sex-Dependent Circuit That Promotes Dense Strong Bones in Female Mice.
Candice B Herber,William C Krause,Liping Wang,James R Bayrer,Alfred Li,Matthew T Schmitz,Aaron Fields,Breanna Ford,Michelle S Reid,Daniel K Nomura,Robert A Nissenson,Stephanie M Correa,Holly A Ingraham bioRxiv, 2018

Developmental Mechanisms Linking Form and Function During Jaw Evolution.
Katherine C Woronowicz,Stephanie E Gline,Safa T Herfat,Aaron J Fields,Richard A Schneider bioRxiv, 2018

Structure-function relationships at the human spinal disc-vertebra interface.
Berg-Johansen B, Fields AJ, Liebenberg EC, Li A, Lotz JC Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2017

Role of Osteoblast Gi Signaling in Age-Related Bone Loss in Female Mice.
Millard SM, Wang L, Wattanachanya L, O'Carroll D, Fields AJ, Pang J, Kazakia G, Lotz JC, Nissenson RA Endocrinology, 2017

Glucocorticoid suppression of osteocyte perilacunar remodeling is associated with subchondral bone degeneration in osteonecrosis.
Fowler TW, Acevedo C, Mazur CM, Hall-Glenn F, Fields AJ, Bale HA, Ritchie RO, Lotz JC, Vail TP, Alliston T Scientific reports, 2017

Pathobiology of Modic changes.
Dudli S, Fields AJ, Samartzis D, Karppinen J, Lotz JC European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2016

Alterations in intervertebral disc composition, matrix homeostasis and biomechanical behavior in the UCD-T2DM rat model of type 2 diabetes.
Fields AJ, Berg-Johansen B, Metz LN, Miller S, La B, Liebenberg EC, Coughlin DG, Graham JL, Stanhope KL, Havel PJ, Lotz JC Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2015

Trabecular plates and rods determine elastic modulus and yield strength of human trabecular bone.
Wang J, Zhou B, Liu XS, Fields AJ, Sanyal A, Shi X, Adams M, Keaveny TM, Guo XE Bone, 2014

Comparison of vertebral and intervertebral disc lesions in aging humans and rhesus monkeys.
Bailey JF, Fields AJ, Liebenberg E, Mattison JA, Lotz JC, Kramer PA Osteoarthritis and cartilage, 2014

Structural parameters determining the strength of the porcine vertebral body affected by tumours.
Sahli F, Cuellar J, Pérez A, Fields AJ, Campos M, Ramos-Grez J Computer methods in biomechanics and biomedical engineering, 2014

Innervation of pathologies in the lumbar vertebral end plate and intervertebral disc.
Fields AJ, Liebenberg EC, Lotz JC The spine journal : official journal of the North American Spine Society, 2013

The role of the vertebral end plate in low back pain.
Lotz JC, Fields AJ, Liebenberg EC Global spine journal, 2013

Influence of biochemical composition on endplate cartilage tensile properties in the human lumbar spine.
Fields AJ, Rodriguez D, Gary KN, Liebenberg EC, Lotz JC Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2013

Vertebral fragility and structural redundancy.
Fields AJ, Nawathe S, Eswaran SK, Jekir MG, Adams MF, Papadopoulos P, Keaveny TM Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2012

Micromechanics of the human vertebral body for forward flexion.
Yang H, Nawathe S, Fields AJ, Keaveny TM Journal of biomechanics, 2012

Trabecular architecture and vertebral fragility in osteoporosis.
Fields AJ, Keaveny TM Current osteoporosis reports, 2012

Individual Trabecula Segmentation (ITS)-Based Plate-Rod Microstructural Finite Element Model Predicts Nonlinear Mechanical Properties of Human Trabecular Bone.
Bin Zhou,Ji Wang,Arnav Sanyal,Aaron J. Fields,Hong Wang,Tony M. Keaveny,Baohua Ji,X. Sherry Liu,X. Edward Guo , 2012

Influence of vertical trabeculae on the compressive strength of the human vertebra.
Fields AJ, Lee GL, Liu XS, Jekir MG, Guo XE, Keaveny TM Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2011

Bone Biomechanical Behavior in Adult Mice is Regulated by Osteoblast Gi Signaling in a Sex- and Site-Specific Manner.
Aaron J. Fields,Susan M. Millard,Jeannie F. Bailey,Dylan O’Carroll,Jeffrey C. Lotz,Robert A. Nissenson , 2011

Mechanisms of initial endplate failure in the human vertebral body.
Fields AJ, Lee GL, Keaveny TM Journal of biomechanics, 2010

Role of trabecular microarchitecture in whole-vertebral body biomechanical behavior.
Fields AJ, Eswaran SK, Jekir MG, Keaveny TM Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2009

Multi-scale modeling of the human vertebral body: comparison of micro-CT based high-resolution and continuum-level models.
Eswaran SK, Fields AJ, Nagarathnam P, Keaveny TM Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 2009

Effects of knee simulator loading and alignment variability on predicted implant mechanics: a probabilistic study.
Laz PJ, Pal S, Fields A, Petrella AJ, Rullkoetter PJ Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2006